How metabolic syndrome causes the Diabetes 2 and cardiovascular diseases?(the biochemistry of this).

Required

Write about how metabolic syndrome causes the Diabetes 2 and cardiovascular diseases?(the biochemistry of this).
Also write about the relation between Metabolic syndrome and Obesity.
Also  use papers of the last 5 years. Kindly , this work should critical and give you opinion in some points .I would like you to take the following points into account:
• Demonstrate a depth of knowledge associated with the review title . Special focus is required on contemporary literature and up to date referencing
• Provide expert commentary on assignment (as guided by Expert Reviews journal series)
• Provide 5 year view of subject area –
• Provide appropriate and up to date referencing, including brief descriptions of all references with of special (*) and outstanding (**) interest highlighted accordingly.
• You have to use PUBMED website and googlr shcolar . i would like to write 12 pages exclude the refrences  page ,also i need you to write the refrences  (Harvard STYLE ) 
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